|
|
lab profile
 |
Linda Holland University of California San Diego
9500 Gilman Drive -0202
La Jolla, California 92093
USA
lzholland@ucsd.edu
858-534-5607
|
| PI: |
YES |
| Taxa Studied: |
Invertebrate Animals, amphioxus, cephalochordates |
| Techniques Employed: |
Degenerate PCR, Solexa (Illumina) Sequencing, SOLiD Sequencing, In Situ Hybridization, Antibody Staining, Sectioning for Histology, Sectioning for Electron Microscopy, Epifluoresence Microscopy, Transgenesis, Morpholinos, evolution of development, developmental mechanisms, chordate evolution |
| Research Description: |
I pioneered evo-devo research on amphioxus. Our overall question is how the vertebrates evolved from their invertebrate ancestors. To that end, we use amphioxus as a proxy for the common ancestor of amphioxus and the vertebrates. At present we are studying two species, Branchiostoma floridae and Asymmetron lucayanum. We are breeding both species out of season in the laboratory. I am focusing on evolution of the nervous system and early development including left/right asymmetry as well as alternative splicing. We are doing transcriptomics and sequencing the Asymmetron genome. |
| Lab Web Page: |
|
| Willing to Host Undergraduates: |
YES |
| Actively Seeking Undergraduates: |
NO |
|
|
